Pregnancy requires profound metabolic and cardiovascular adaptations by the maternal organism. Disruption of these adaptive processes can lead to serious pregnancy complications such as preeclampsia, which adversely affect both maternal health and fetal development.
Our research group investigates how the placenta, the vascular system, and maternal metabolism interact and how these interactions contribute to pregnancy disorders. Our goal is to identify disease-relevant signaling pathways and translate this knowledge into novel diagnostic and therapeutic strategies.
A current focus of our work is preeclampsia, one of the leading causes of maternal and perinatal morbidity worldwide. By combining clinical cohorts, advanced molecular analyses, and human-based experimental models, we aim to better understand the biological mechanisms underlying this disease and to develop new therapeutic approaches.
